Phenylcarbamic acid esters
Medchemexpress LLC 4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester | 1309460-29-4 | ≥98.0% | C18H34O9 | 1 G
Acid-PEG5-C2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules containing two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for a target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Target PROTAC linkers
- PROTAC pathway
- Biochemicals category
- For research use only (RUO)
- Cancer research field
- Solubility: 10 mM in DMSO
- IC50 and target: PEGs, Alkyl/ether
![eMolecules 220210-56-0 | 3-[t-Butoxycarbonyl]phenylboronic acid | Synthonix - Stock | MFCD01630855 | 222.050 | C11H15BO4 | 98.000 | CC(C)(C)OC(=O)c1cccc(c1)B(O)O | 25g | 525908570](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169773.jpg-250.jpg)
eMolecules 220210-56-0 | 3-[t-Butoxycarbonyl]phenylboronic acid | Synthonix - Stock | MFCD01630855 | 222.050 | C11H15BO4 | 98.000 | CC(C)(C)OC(=O)c1cccc(c1)B(O)O | 25g | 525908570
3-[t-Butoxycarbonyl]phenylboronic acid | Synthonix - Stock | 220210-56-0 | MFCD01630855 | 222.050 | C11H15BO4 | 98.000 | CC(C)(C)OC(=O)c1cccc(c1)B(O)O | 25g | 525908570
Medchemexpress LLC (±)-Boc-α-phosphonoglycine trimethyl ester | 89524-98-1 | 297.24 | 50 G
(±)-Boc-α-phosphonoglycine trimethyl ester functions as a glycine equivalent and donor in organic synthesis. Its reaction byproducts are water-soluble and easily purified. It facilitates the efficient synthesis of 5,6- and 5,8-dimethoxy-substituted ester products via four mild reactions.
- Serves as a glycine equivalent and glycine donor
- Possesses strong α-proton acidity
- Reaction byproducts are water-soluble and easy to purify
- Used to efficiently obtain 5,6- and 5,8-dimethoxy-substituted ester products
- Achieved through four mild reactions
Medchemexpress LLC 5-(Boc-amino)pentanoic acid | 27219-07-4 | MFCD00076903 | 99.9% | 217.26 g·mol-1 | C10H19NO4 | 5 G
Boc-NH-C4-acid is a Boc-protected 5-aminovaleric acid used as an alkyl linker in PROTAC and medicinal chemistry applications. It contains a Boc-protected amine and a terminal carboxylic acid, allowing orthogonal coupling and downstream deprotection. Molecular formula C10H19NO4; molecular weight 217.26 g·mol-1. High nominal purity supports synthetic workflows.
- Boc-protected amine enables temporary protection during multi-step synthesis.
- Terminal carboxylic acid allows efficient amide coupling reactions.
- Suitable for PROTAC linker assembly and linker optimization studies.
- High nominal purity (99.85%) for reliable reproducibility.
- Available in bench-scale quantities for research use.
Medchemexpress LLC Boc-cycloleucine | 35264-09-6 | 229.27 | 10 G
Boc-cycloleucine is a biochemical reagent that serves as a valuable biological material or organic compound for life science research. It is typically supplied as a white to off-white solid.
- Used as a biological material for research
- Organic compound for life science studies
- Suitable for various research applications
- Solid, white to off-white appearance
- For research use only
eMolecules 1255666-48-8 | 1-N-Boc-4-amino-3,3-difluoro-piperidine | J & W PharmLab LLC | MFCD16250242 | 236.263 | C10H18F2N2O2 | 96.000 | CC(C)(C)OC(=O)N1CCC(N)C(F)(F)C1 | 5g | 443433294
1-N-Boc-4-amino-3,3-difluoro-piperidine | J & W PharmLab LLC | 1255666-48-8 | MFCD16250242 | 236.263 | C10H18F2N2O2 | 96.000 | CC(C)(C)OC(=O)N1CCC(N)C(F)(F)C1 | 5g | 443433294
Sigma Aldrich Fine Chemicals Biosciences Rat Dorsal Root Ganglion N
Rat Dorsal Root Ganglion Neurons (RDRGN) are derived from spinal cords of normal embryonic rat (gestation day 15). 500 000 cells cryopreserved in Serum-free Freezing Medium.
Medchemexpress LLC N-(PEG2-Boc)-N-bis(PEG2-propargyl) | 2100306-69-0 | 485.61 | 50 MG
N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing azide groups.
- It is a PEG-based PROTAC linker.
- It can be used in the synthesis of PROTACs.
- It is a click chemistry reagent.
- It contains an alkyne group.
- It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.
Medchemexpress LLC N-Boc-N-bis(PEG4-acid) | 2093152-88-4 | 97.0% | C27H51NO14 | 25 MG
N-Boc-N-bis(PEG4-acid) is a PROTAC linker, specifically a PEG-based type, designed for use in the synthesis of PROTACs. PROTACs are compounds that utilize the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins. This is achieved by connecting two different ligands via a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets the protein intended for degradation.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- PROTACs employ the ubiquitin-proteasome system to degrade target proteins.
- PROTACs consist of two ligands connected by a linker, targeting an E3 ubiquitin ligase and a protein of interest.
Medchemexpress LLC β-N-Acetylhexosaminidase, Porcine kidney | 9012-33-3 | 50 U
β-N-Acetylhexosaminidase, Porcine kidney is a glycosidase with transglycosylation activity. It is utilized to produce beneficial human milk oligosaccharides and interacts effectively with low molecular weight sugar alcohols such as glycerol, erythritol, and xylitol.
- Demonstrates optimal activity at pH 5 and 40 °C
- Maintains high thermal stability (up to 55°C) when attached to the cell wall
- Shows promise for applications in the biotransformation of Chitin
- Useful in research within the food health sector
Medchemexpress LLC 4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester | 1309460-29-4 | ≥98.0% | C18H34O9 | 50 MG
Acid-PEG5-C2-Boc is a chemical compound with the molecular formula C18H34O9 and a molecular weight of 394.46. It is supplied in liquid form, ranging from colorless to light yellow. This product has a purity of ≥98.0% as determined by NMR spectroscopy, and its 1H NMR spectrum is consistent with its structure.
- Colorless to light yellow liquid appearance
- High purity of ≥98.0% by NMR
- 1H NMR spectrum consistent with structure
Cambridge Isotope Laboratories JECS PCB/POPs/PBDE native in nonane 1 2 mL
JECS PCB/POPs/PBDE native in nonane 1 2 mL
Medchemexpress LLC N-Isopropylacrylamide-d7 | 1219803-32-3 | 98.1% | 120.20 | 1 MG
N-Isopropylacrylamide-d7 is the deuterium labeled N-Isopropylacrylamide. It is intended for research use only and can be utilized as a tracer or as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS. Deuterium substitution has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis.
- Applicable in NMR, GC-MS, or LC-MS.
- Deuterium substitution may impact pharmacokinetic and metabolic profiles.
Medchemexpress LLC CXCR4 Human N-His- 10ug
Recombinant human CXCR4 fragment (residues P303-S352) expressed in E. coli and provided with N-terminal His and SUMO tags and a C-terminal Myc tag. The protein is supplied as a purified fragment (~28 kDa, >90% purity) intended for biochemical and cell-based studies of CXCR4-CXCL12 interactions, receptor signaling, and protein-protein interaction assays.
- Expressed in E. coli for consistent recombinant production.
- Contains N-terminal His and SUMO tags and a C-terminal Myc tag.
- Fragment corresponds to residues P303-S352 of human CXCR4.
- Approximately 28 kDa molecular weight.
- Purity greater than 90% by reducing SDS-PAGE.
- Supplied in 10 μg size suitable for assay development and binding studies.